The Chinese herb, known as Radix Astragali ('root of Astragalus') in western herbal medicine, manufactures many types of natural products. Among these the main active substances are its antioxidant flavonoids and several sterol derivatives called astragalosides. At this time one of the very most fruitful areas of research on Radix Astragali entails the potential that astragalosides show for slowing aging.
One of the astragalosides, astragaloside IV, yields a substance called cycloastragenol. This molecule provides a defensive leaders online shop effect for chromosomes during cellular reproduction. Such an effect is at the heart of one of the hottest topics in anti-aging research. Indeed, drug companies are hurrying to discover synthetic analogues to cycloastragenol that can be patented as anti-aging drugs. Three recent studies on cycloastragenol already point to its potential health benefits. One study, at Beijing University of Chinese Medicine, showed how cycloastragenol can suppress the formation of new fat cells. This activity might be of benefit for treating obesity. This role supports the utilization of Radix Astragali being an oral supplement. Another two studies give attention to metabolism in skin cells. Research from the Hong Kong University of Science and Technology, unearthed that cycloastragenol can stimulate a vital anti-aging enzyme known from human keratinocytes. Keratinocytes are the most abundant cells in the skin we have, creating about 90% of its outermost layer. Stimulating keratinocyte metabolism provides a base for healthy, radiant skin. Finally, scientists at the College of Oriental Medicine at Kyung Hee University in South Korea have shown the prospect of extracts of Radix Astragali for protecting the skin against damage by UV light. The concern with such damaging radiation is that it accelerates aging and might even lead to DNA damage and subsequent skin cancer. In the South Korean study, extracts of Radix Astragali stopped the increasing loss of pre-collagen in fibroblasts that have been exposed to damaging UV light. Extracts were found to inhibit an enzyme called collagenase, which stops working or stops the formation of collagen. Collagen is needed for healthy skin since it's the main structural protein that holds skin cells together. UV light causes its destruction, and Astragalus root extracts prevent that destruction.
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